PRODUCT NAME
BULMECTIN 0.2% 50 GR
COMPOSITION
Avermectin - 0.2 g
Lactose - 50 - 80 g
Silicon oxide - 0.5 - 0.9 g
Mycelium mass - up to 100 g
ACTION
Avermectin has a simultaneous endo and ectoparasitic action, it causes paralysis of nematodes, arthropods and insects, blocks the conduction of nerve impulses at the level of interneuronal synapses in nematodes and at the level of neuromuscular synapses in arthropods.
The effect is achieved by stimulating the release of gamma-aminobutyric acid (AGAB) in the presynaptic ending and its binding to the postsynaptic receptors, resulting in the cessation of the transmission of nerve impulses, with paralysis and death of the parasite.
Trematodes and cestodes are not affected, for them AGAB does not intervene as an interneuronal mediator. It is well tolerated by mammals, in which AGAB is located only in the CNS, where avermectin cannot penetrate. This product is harmless for pregnant females and newborns.
INDICATIONS
For large ruminants: in the treatment of gastrointestinal infestations with long nematodes (osterstagia, haemoncus, trichostrongylus, cooperius, parafilaria, esophagostomus,
bunostmus, nemathodirus, dictyocaulus), in the treatment of infestations with grass ticks, lice, sarcoptic mange and psoroptic mange, hypodermosis.
For small ruminants: in the treatment of gastrointestinal infestations with long nematodes (haemonchus, ostertagia, trichostrongylus, cooperius, esophagostomus, nemathodirus, strongylus, chabertia, trichuris), in the treatment of infestations with ticks, melophagus and oestrus.
For horses: in the treatment of strongylosis, parascariosis, trichostrongylosis, chabertiosis, microfilariosis.
For pigs: in the treatment of ascaridosis, strongylosis, hyostrongylosis, metastrongylosis, esophagostomosis, infestation with ticks, lice, sarcoptic mange.
CONTRAINDICATIONS
This product is not indicated to be administered to animals other than those specified.
METHOD OF ADMINISTRATION
Orally, mixed with 1/2 or 1/3 of the amount of food from a meal - a single administration. The staff must be warned to wear protective gloves during preparation.
DOSAGE
The average dose is 0.002 g/kg/m3 of pure avermectin.
For pigs - 1.5 g/ 10 kg/ mc
For large and small ruminants - 1 g/ 10 kg/ mc
For horses - 1 g/ 10 kg/ mc
For sheep with scabies - 2 g/ 10 kg/ mc
WAITING TIME
For large and small ruminants:
- for meat - 21 days
- for milk - 14 days
For pigs - 14 days
