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CARDALIS 5 MG / 40 MG - 30 TABLETS // congestive heart failure// DOGS

CARDALIS 5 MG / 40 MG - 30 TABLETS // congestive heart failure// DOGS

Prix habituel € 89.99 EUR
Prix habituel Prix promotionnel € 89.99 EUR
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Frais d'expédition calculés à l'étape de paiement.

Important: Cardalis 5 mg / 40 mg - 30 Tablets belongs to the veterinary pharmacy category. Consult the veterinarian for diagnosis, prescription of medication or diet according to the specific needs of your dog (cat).

Cardalis 5 mg / 40 mg is a brown, palatable oral tablet with an elongated shape and a median line, used for the treatment of congestive heart failure.

Manufacturer: Ceva Sante
DCI: Benazepril/Benazepril HCI, Spironolactone/Spironolactone

NAME OF THE VETERINARY MEDICINAL PRODUCT

Cardalis 5mg / 40mg tablets for dogs.

Benazepril hydrochloride 5mg. spironolactone 40mg.

DECLARATION OF ACTIVE SUBSTANCES AND OTHER INGREDIENTS (INGREDIENTS):

Cardalis is a brown, palatable oral tablet with an elongated shape and a median line.

Benazepril hydrochloride (HCL)

(benazepril HCL)

spironolactone

(spironolactone)

 

INDICATIONS:

For the treatment of congestive heart failure caused by chronic valvular degeneration, in dogs (with diuretic support when necessary).

CONTRAINDICATIONS:

Do not administer during pregnancy and lactation.

Do not administer to animals used in the mountains or to those that are intended to be used for the mountains.

Do not administer to dogs suffering from hypoadenocorticism, hyperkalemia or hyponatremia.

Do not use in combination with non-steroidal anti-inflammatory drugs (NSAIDs) in dogs with renal failure.

Do not use in case of hypersensitivity to Angiotensin Converting Enzyme inhibitors (ACE inhibitors) or to any of the excipients.

Do not use in case of heart failure caused by aortic or pulmonary stenosis.

ADVERSE REACTIONS:

Male dogs treated with spironolactone frequently experience atrophy of the prostate, which is reversible.

TARGET SPECIES:

Dogs.

DOSAGE FOR EACH SPECIES, ROUTE(S) OF ADMINISTRATION AND MODE OF ADMINISTRATION:

This combination of active substances of the product must be used only in dogs that require both active substances to be administered simultaneously in this fixed dose.

Oral administration.

Cardalis tablets should be administered once a day, at a dosage of 2mg. spironolactone per kg. live weight and 0.25 mg./kg. benazepril hydrochloride (HCL) live weight, according to the table below.

 

Benazepril hydrochloride (HCL)

(benazepril HCL)

spironolactone

(spironolactone)

Cardalis 2.5 mg./20 mg. tablets for dogs 2.5 mg. 20 mg.
Cardalis 5 mg./40 mg. tablets for dogs   5 mg. 40 mg.
Cardalis 10 mg./80 mg. tablets for dogs 10 mg. 80 mg.
 

 
RECOMMENDATIONS REGARDING CORRECT ADMINISTRATION:

The product must be administered with food. The tablet can be mixed with a small amount of food and given before the main meal or in food. The tablets are flavored.

SPECIAL WARNINGS:

Special precautions for use in animals.

Before initiating treatment with spironolactone and benazepril HCL, an assessment of kidney function and serum potassium levels must be made, especially in elderly dogs that may suffer from hypoadrenocorticism, hyperkalemia or hyponatremia. Unlike humans, in dogs no increase in the incidence of hyperkalemia was observed in the case of clinical tests performed with this combination. However, regular monitoring of renal function and serum potassium level is recommended in the case of dogs with kidney disease, as they present an increased risk of hyperkalemia during treatment with this product.

Spironolactone has an antiandrogenic effect and therefore it is not recommended to administer the product to growing dogs.

Since spironolactone undergoes biotransformation at the liver level, the product must be carefully administered to dogs with liver dysfunctions.

OVERDOSE:

After administration of a dose 10 times higher than the recommended dosage (20 mg./kg.gvspironolactone and 2.5 mg./kg.gvbenazepril HCL) dose-dependent adverse effects were reported in healthy dogs. Daily administration to healthy dogs of an overdose, e.g. 6 times higher (12 mg./kg. live weight spironolactone and 1.5 mg./kg. live weight benazepril HCL) and 10 times higher (20 mg./kg gvspironolactone and 2.5 mg./kg .gv benazepril HCL) than the therapeutic dose led to a reduction in red cell mass. However, this decrease is transient, the mass of red cells remaining in normal values, the finding was not considered important from a clinical point of view. A moderate compensatory physiological hypertrophy of the glomerular zone of the adrenal glands was found, dose-dependent change. This hypertrophy does not seem to have pathological implications because it is reversible once the treatment is stopped. In case of accidental ingestion by the dog of a large number of Cardalis tablets, there is no specific antidote or treatment, it is recommended to induce vomiting, wash the stomach (after risk assessment) and monitor electrolytes. Symptomatic treatment, rehydration must be carried out.

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CARDALIS 5 MG / 40 MG - 30 TABLETS // congestive heart failure// DOGS
CARDALIS 5 MG / 40 MG - 30 TABLETS // congestive heart failure// DOGS
CARDALIS 5 MG / 40 MG - 30 TABLETS // congestive heart failure// DOGS
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<span class=money>€ 89.99</span>/pièce € 0.00