VIBROCIL Duo nasal spray solution, 10ml, Haleon

Therapeutic indications:

Symptomatic treatment of nasal congestion and rhinorrhea associated with coryza.

List of excipients: disodium edetate dihydrate, glycerol 85%, concentrated hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment), purified water.

Ingredients: 1 ml contains xylometazoline hydrochloride 0.5 mg and ipratropium bromide 0.6 mg. 1 puff (approximately 140 microliters) contains xylometazoline hydrochloride 70 micrograms and ipratropium bromide 84 micrograms.

How to use: Before the first administration, prime the pump by pressing 4 times. Once the pump is primed, it will remain ready to operate throughout the daily treatment. If the spray solution is not sprayed when the pump is fully pressed or the medicine has not been used for more than 6 days, the pump must be re-primed by pressing 4 times as the first time.

• Adults: 1 puff in each nostril, up to 3 times a day. An interval of at least 6 hours must be maintained between the administration of two doses. Do not exceed 3 applications per day in each nostril. The duration of treatment should not exceed 7 days. It is recommended to stop treatment when symptoms improve, even before the maximum duration of treatment of 7 days, in order to minimize the risk of side effects.
• Children and adolescents: Vibrocil Duo is not recommended for use in children and adolescents under 18 years of age due to insufficient data on safety and efficacy.
• Elderly: there is only limited experience with use in patients over 70 years of age. 

Warnings and precautions:

The drug should be administered with caution to patients with: hypertension, cardiovascular diseases - hyperthyroidism, diabetes mellitus - prostatic hyperplasia, inter-ureteral plica stenosis, pheochromocytoma. Caution is recommended in patients prone to: angle-closure glaucoma - epistaxis (e.g. the elderly) - paralytic ileus - cystic fibrosis.

Contraindications:

Vibrocil Duo should not be used in children and adolescents under 18 years of age due to insufficient data on safety and efficacy. Hypersensitivity to the active substances or to any of the excipients. Known hypersensitivity to atropine or similar substances, e.g. hyoscyamine and scopolamine. After surgical interventions in which the dura mater may have been penetrated, e.g. transsphenoidal hypophysectomy or other transnasal interventions. In patients with glaucoma. In patients with dry rhinitis.

Presentation form:  10ml nasal spray.